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Adults: Usual Dose: 300 mg daily orally on an empty stomach.
Children: 5 mg/kg body weight daily. Maximum Dose: 300 mg daily.
Intermittent Therapy: 10 mg/kg body weight 3 times weekly or 15 mg/kg body weight twice weekly. Maximum Dose: 900 mg.
Doses may need to be reduced in patients with hepatic impairment or moderate to severe renal impairment.
Tuberculosis Prophylaxis: Daily dose of 300 mg are given for at least 6 months and sometimes for up to 1 year.
